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Cerebral “Dirty-Appearing” White Matter and Its Link to Cognitive Decline and Dementia Risk
Posted inNeurology news Public Health

Cerebral “Dirty-Appearing” White Matter and Its Link to Cognitive Decline and Dementia Risk

Posted by By MedXY 05/13/2026
In older adults with limited small vessel disease, “dirty-appearing” white matter on MRI was not linked to baseline cognition, cognitive decline, or dementia risk, unlike conventional white matter hyperintensities.
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Staging Intermediate Hyperglycaemia to Improve Type 2 Diabetes Prevention: Findings from the ELSA-Brasil Study
Posted inDiabetes & Endocrinology news Public Health

Staging Intermediate Hyperglycaemia to Improve Type 2 Diabetes Prevention: Findings from the ELSA-Brasil Study

Posted by By MedXY 05/13/2026
The ELSA-Brasil study found that staging intermediate hyperglycaemia with fasting glucose plus 1-hour glucose better predicted type 2 diabetes than fasting glucose plus HbA1c, and a clinical risk score reduced unnecessary testing.
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Weight Regain Can Reverse the Metabolic Benefits of Caloric Restriction: Insights From CALERIE-2
Posted inDiabetes & Endocrinology news Public Health

Weight Regain Can Reverse the Metabolic Benefits of Caloric Restriction: Insights From CALERIE-2

Posted by By MedXY 05/13/2026
CALERIE-2 post hoc analysis found that weight regain after caloric restriction can reverse improvements in insulin and IGF-1 signaling, while sustained weight loss preserves metabolic benefits and may lower biological aging markers.
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Rates of Systemic Treatment for Metastatic Non-Small Cell Lung Cancer Among Older Adults
Posted innews Oncology Public Health

Rates of Systemic Treatment for Metastatic Non-Small Cell Lung Cancer Among Older Adults

Posted by By MedXY 05/12/2026
A population-based study of older adults with metastatic NSCLC found that fewer than half received systemic treatment, with only slight improvement over time. Oncology referral and biomarker testing were strongly linked to treatment, while advanced age and barriers to care lowered access.
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Systemic Treatment Remains Underused in Older Adults With Metastatic Non-Small Cell Lung Cancer
Posted innews Oncology Public Health

Systemic Treatment Remains Underused in Older Adults With Metastatic Non-Small Cell Lung Cancer

Posted by By MedXY 05/12/2026
A large SEER-Medicare study found that fewer than half of older adults with metastatic NSCLC received systemic therapy, with only modest improvement from 2006 to 2021. Specialist referral and biomarker testing were strongly linked to treatment receipt.
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Obesity Counseling Is Still Missed in Most US Office Visits, With Older Adults Least Likely to Receive Advice
Posted inFamily Medicine & Nutrition news Public Health

Obesity Counseling Is Still Missed in Most US Office Visits, With Older Adults Least Likely to Receive Advice

Posted by By MedXY 05/12/2026
A national analysis of US office visits found that obesity counseling remains uncommon, with only 40.1% of visits including any counseling and 12.2% including weight, diet, and exercise advice together.
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Low-Dose Aspirin’s Pregnancy Benefit Appears Unchanged by Start Time or Adherence in a Large Multicentre Post Hoc Trial Analysis
Posted innews OB/GYN & Women’s Health Public Health

Low-Dose Aspirin’s Pregnancy Benefit Appears Unchanged by Start Time or Adherence in a Large Multicentre Post Hoc Trial Analysis

Posted by By MedXY 05/11/2026
In this post hoc analysis of a large randomized pregnancy trial, aspirin’s effects on preterm birth and perinatal mortality were not meaningfully modified by gestational age at initiation or measured adherence.
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Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank
Posted inNeurology news Public Health

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank

Posted by By MedXY 05/10/2026
In nearly 483,000 UK Biobank participants, sarcopenia, low grip strength, and slow walking pace were associated with higher risks of incident stroke and poorer survival after stroke.
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Multi-ancestry Polygenic Risk Scores Substantially Improve Type 2 Diabetes Risk Prediction Across Diverse Populations
Posted inDiabetes & Endocrinology news Public Health

Multi-ancestry Polygenic Risk Scores Substantially Improve Type 2 Diabetes Risk Prediction Across Diverse Populations

Posted by By MedXY 05/10/2026
A large multi-ancestry study shows that publicly available polygenic risk scores improve prediction of type 2 diabetes onset and selected microvascular complications across major global ancestry groups.
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Household Income Decline and Job Loss Among Survivors of Critical Illness: A Nationwide Cohort Study
Posted inCritical Care news Public Health

Household Income Decline and Job Loss Among Survivors of Critical Illness: A Nationwide Cohort Study

Posted by By MedXY 05/09/2026
A large South Korean study reveals critical illness survivors face severe socioeconomic consequences, with 27.6% experiencing income decline and 12.3% job loss within a year, disproportionately affecting high-income households despite universal health coverage.
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Ethnicity Influences Relapse-Free Survival in Immune-Mediated Thrombotic Thrombocytopenic Purpura
Posted inHematology-Oncology news Public Health

Ethnicity Influences Relapse-Free Survival in Immune-Mediated Thrombotic Thrombocytopenic Purpura

Posted by By MedXY 05/09/2026
A French study reveals African ancestry significantly increases relapse risk in iTTP patients treated with rituximab. Key risk factors include male sex and prior relapses, with implications for personalized monitoring strategies.
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Whole-Genome Sequencing Suggests Casual Community Contact Drives Much of Drug-Resistant Tuberculosis Transmission in Durban
Posted inInfectious Diseases news Public Health

Whole-Genome Sequencing Suggests Casual Community Contact Drives Much of Drug-Resistant Tuberculosis Transmission in Durban

Posted by By MedXY 05/09/2026
A molecular epidemiology study in Durban found that casual community contact, not only household or named contacts, accounted for a substantial share of drug-resistant tuberculosis transmission.
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Most Patients Reach 20/40 After Cataract Surgery, but the Current MIPS Success Metric May Misclassify Quality and Exclude Nearly Half of Cases
Posted innews Ophthalmology Public Health

Most Patients Reach 20/40 After Cataract Surgery, but the Current MIPS Success Metric May Misclassify Quality and Exclude Nearly Half of Cases

Posted by By MedXY 05/09/2026
A large multicenter study found that MIPS measure 191 captures high cataract surgery success rates but excludes many patients and may require case-mix adjustment to support fair surgeon comparisons.
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Large Multi-Center EMR Cohort Suggests NSAID Exposure Is Associated With Lower Future Risk of Age-Related Macular Degeneration
Posted innews Ophthalmology Public Health

Large Multi-Center EMR Cohort Suggests NSAID Exposure Is Associated With Lower Future Risk of Age-Related Macular Degeneration

Posted by By MedXY 05/08/2026
In a large TriNetX retrospective cohort, prescribed NSAID use was associated with a lower subsequent risk of AMD, including both non-exudative and exudative disease, though residual confounding limits causal inference.
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HPV Self-Sampling May Expand Cervical Cancer Screening Access for Transmasculine and Nonbinary Patients
Posted innews OB/GYN & Women’s Health Public Health

HPV Self-Sampling May Expand Cervical Cancer Screening Access for Transmasculine and Nonbinary Patients

Posted by By MedXY 05/07/2026
A narrative review suggests HPV self-sampling is acceptable and potentially practice-changing for transmasculine and nonbinary people who are often underscreened for cervical cancer.
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Type 1 Diabetes in Sweden Clusters in Rural Areas, With Early-Childhood Geography Showing the Strongest Signal
Posted inDiabetes & Endocrinology news Public Health

Type 1 Diabetes in Sweden Clusters in Rural Areas, With Early-Childhood Geography Showing the Strongest Signal

Posted by By MedXY 05/07/2026
A nationwide Swedish cohort study found marked geographic variation in type 1 diabetes incidence, with the strongest clustering linked to residential location during the first 5 years of life and higher risk in rural, forested, and agricultural areas.
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Education and Neighborhood Resources Explain Much of the Racial and Ethnic Gap in Timely Dementia Diagnosis
Posted inNeurology news Public Health

Education and Neighborhood Resources Explain Much of the Racial and Ethnic Gap in Timely Dementia Diagnosis

Posted by By MedXY 05/05/2026
Among older U.S. adults with dementia, non-Hispanic Black and Hispanic individuals were significantly less likely than non-Hispanic White individuals to receive a timely diagnosis, with education and neighborhood affluence explaining much of the disparity.
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Medicare’s Oncology Care Model Did Not Increase Systemic Therapy Starts and Was Linked to Lower Use in Poor-Prognosis Cancer
Posted innews Oncology Public Health

Medicare’s Oncology Care Model Did Not Increase Systemic Therapy Starts and Was Linked to Lower Use in Poor-Prognosis Cancer

Posted by By MedXY 05/05/2026
A matched difference-in-differences study found that the Oncology Care Model did not increase systemic therapy initiation overall and was associated with lower treatment initiation and lower spending in poor-prognosis cancers.
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“Never More Than 15 Feet From the Respirator”: Housestaff Research During the 1955 Boston Polio Epidemic
Posted inInfectious Diseases news Public Health

“Never More Than 15 Feet From the Respirator”: Housestaff Research During the 1955 Boston Polio Epidemic

Posted by By MedXY 05/05/2026
During Boston's devastating 1955 polio epidemic, Massachusetts General Hospital trainees conducted groundbreaking patient research while providing round-the-clock care in iron lung wards – a striking contrast to trainee roles during COVID-19.
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Ergonomic Strain Is Common in Otolaryngology Surgery, With Pain Rising as Cases Become More Difficult and Prolonged
Posted innews Otorhinolaryngology Public Health

Ergonomic Strain Is Common in Otolaryngology Surgery, With Pain Rising as Cases Become More Difficult and Prolonged

Posted by By MedXY 05/04/2026
A prospective study found frequent medium-to-high ergonomic risk and measurable postoperative pain among otolaryngology surgeons, highlighting modifiable occupational hazards in routine head and neck surgery.
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