Beyond Child Survival: The Evolving Global Burden of Lower Respiratory Infections and Emerging Pathogens (1990-2023)

Beyond Child Survival: The Evolving Global Burden of Lower Respiratory Infections and Emerging Pathogens (1990-2023)

The GBD 2023 study highlights a 33.4% reduction in pediatric LRI mortality since 2010, yet 2.5 million annual deaths persist. While Streptococcus pneumoniae remains the primary pathogen, newly modeled aetiologies like non-tuberculous mycobacteria now account for 22% of the total LRI mortality burden.
Culturally Tailored Community Health Worker Support Mitigates Interdialytic Weight Gain in Hispanic and Latino Hemodialysis Patients

Culturally Tailored Community Health Worker Support Mitigates Interdialytic Weight Gain in Hispanic and Latino Hemodialysis Patients

The Navigate-Kidney trial demonstrates that community health worker support significantly improves interdialytic weight gain, dialysis adherence, and patient activation among Hispanic and Latino individuals on hemodialysis, addressing critical social and clinical barriers in kidney care.
Multicomponent Nudges Significantly Boost Influenza Vaccination Rates in Primary Care: Insights from the BE IMMUNE Trial

Multicomponent Nudges Significantly Boost Influenza Vaccination Rates in Primary Care: Insights from the BE IMMUNE Trial

The BE IMMUNE randomized trial demonstrates that combining patient text reminders, clinician EHR pended orders, and peer comparisons increases flu vaccination by 5.1 percentage points among adults aged 50 and older, highlighting the efficacy of multilevel behavioral interventions in clinical settings.
Beyond the Lungs: How Ambient Air Pollution Drives Alzheimer’s Neuropathology and Cognitive Decline

Beyond the Lungs: How Ambient Air Pollution Drives Alzheimer’s Neuropathology and Cognitive Decline

Emerging evidence confirms that air pollution, particularly PM2.5 and NO2, is directly associated with Alzheimer’s neuropathology, structural brain changes, and cognitive decline. New research highlights that these effects are partially mediated by pulmonary function and manifest as increased amyloid-related pathology at autopsy.
Narrowing the Equity Gap: The Impact of California’s 2022 Medicaid Expansion on Access to SGLT-2 Inhibitors and GLP-1 RAs in Older Undocumented Immigrants

Narrowing the Equity Gap: The Impact of California’s 2022 Medicaid Expansion on Access to SGLT-2 Inhibitors and GLP-1 RAs in Older Undocumented Immigrants

This review analyzes the significant shift in type 2 diabetes prescribing patterns following California's 2022 Medi-Cal expansion, highlighting how policy-driven access to SGLT-2 inhibitors and GLP-1 receptor agonists narrowed health equity gaps for older undocumented populations.
The Long Shadow of the ICU: Identifying High-Risk Functional Trajectories in Older Survivors

The Long Shadow of the ICU: Identifying High-Risk Functional Trajectories in Older Survivors

A large-scale longitudinal study reveals that ICU survivors aged 60–79 face significantly higher 5-year excess mortality and functional decline compared to the general population, whereas outcomes for nonagenarians converge with their peers, highlighting a critical window for geriatric intervention and advance care planning.