Diabetes & Endocrinology – Page 10

Thyroxine Therapy in Adult Resistance to Thyroid Hormone Alpha (RTHα): Clinical Efficacy, Safety, and Metabolic Insights

By MedXY 07/08/2026

This analysis reviews a pilot study evaluating high-dose levothyroxine treatment in adult RTHα patients, demonstrating safety, improved quality of life, and distinct metabolic alterations over three years.

Diabetes & Endocrinology news

Unveiling the Role of GIP in Regulating Postprandial Splanchnic Blood Flow in Type 2 Diabetes

By MedXY 07/08/2026

This study reveals that endogenous glucose-dependent insulinotropic polypeptide (GIP) significantly enhances postprandial splanchnic blood flow in people with type 2 diabetes, influencing insulin secretion without affecting glucose levels.

Diabetes & Endocrinology news Radiology

Evolving Paradigms in Diagnosing Cushing’s Disease: Is Bilateral Inferior Petrosal Sinus Sampling Becoming Obsolete?

By MedXY 07/08/2026

Recent evidence indicates that advances in imaging and hormonal testing allow a reduction in the use of bilateral inferior petrosal sinus sampling without compromising diagnostic accuracy in Cushing's disease.

Diabetes & Endocrinology news

Precision Medicine Enhances Management but Not Complications in Young-Onset Diabetes: Insights from the PRISM Randomized Trial

By MedXY 07/08/2026

The PRISM trial evaluated a precision medicine program using biogenetic markers and multidisciplinary care in Chinese young-onset diabetes patients, improving metabolic control and patient well-being but not reducing complications over three years.

Clinical Updates Diabetes & Endocrinology news Public Health

Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

By MedXY 07/08/2026

The HumAn-1 trial found no significant differences between insulin glargine and human isophane insulin in hypoglycemia risk or glucose control in young T1D patients in low-resource settings, underscoring accessibility over insulin type in these contexts.

Diabetes & Endocrinology Internal Medicine news

Harnessing Real-World Evidence to Optimize GLP-1-Based Therapies: Insights from a NIDDK Workshop

By MedXY 07/07/2026

A NIDDK workshop highlighted the crucial role of real-world evidence in addressing gaps about GLP-1 receptor agonists’ safety, effectiveness, adherence, and economic impact to improve clinical and regulatory decision-making.

Diabetes & Endocrinology Gastroenterology news

Development and Validation of a Noninvasive Score for At-Risk Metabolic Dysfunction-Associated Steatohepatitis in Individuals with Obesity Undergoing Bariatric Surgery

By MedXY 07/05/2026

Researchers developed and validated the FMO score, a noninvasive, cost-effective tool to identify at-risk metabolic dysfunction-associated steatohepatitis (MASH) in obese patients, showing strong predictive performance across multiple international cohorts.

Diabetes & Endocrinology news Public Health

Baseline and Longitudinal Joint Associations of Alcohol Consumption and Obesity with Diabetes Risk: Evaluating Multiplicative and Additive Interactions

By MedXY 07/04/2026

This study examines how obesity and alcohol consumption jointly impact diabetes risk over time in an Asian cohort, highlighting differences in interaction measures and implications for diabetes prevention.

Diabetes & Endocrinology news Urology

Pathophysiology-Based Classification of Male Infertility: Transforming Diagnosis and Treatment Through Comprehensive Phenotyping

By MedXY 07/04/2026

This study of 800 men with infertility demonstrates that a detailed pathophysiology-based classification reduces idiopathic cases and identifies distinct endocrine profiles, enabling targeted management.

Diabetes & Endocrinology news Pediatrics

Declining Trends in Impaired Awareness of Hypoglycemia and Severe Hypoglycemia in Youth with Type 1 Diabetes Over Two Decades

By MedXY 07/04/2026

A population-based study reveals a significant reduction in impaired awareness of hypoglycemia and severe hypoglycemia in youth with type 1 diabetes from 2002 to 2024, indicating substantial progress in diabetes care and the ongoing need for routine screening.

Diabetes & Endocrinology Gastroenterology news

Global Insights into MASLD: Predictors of Fibrosis, Clinical Events, and Mortality from the Global-MASLD Study

By MedXY 07/03/2026

The Global-MASLD study identifies key predictors of advanced fibrosis and mortality in metabolic dysfunction-associated steatotic liver disease, highlighting the prognostic value of noninvasive fibrosis markers across diverse populations.

Diabetes & Endocrinology news

Levothyroxine Dosing and the Risk of Suboptimal Thyroid Control: Insights from a Large Real-World Longitudinal Study

By MedXY 07/03/2026

This real-world study demonstrates a dose-dependent increase in suboptimal thyroid hormone control among adults treated with levothyroxine, emphasizing the need for enhanced TSH monitoring in patients on higher doses.

Clinical Updates Diabetes & Endocrinology news

Association of the Primary Aldosteronism Severity Classification with Lateralization and Treatment Outcomes: A Comprehensive Review

By MedXY 07/03/2026

This review synthesizes evidence linking the 2025 Primary Aldosteronism Severity Classification (PASC) with adrenal venous sampling (AVS) lateralization and treatment outcomes, highlighting its potential to enhance precision in PA management.

Diabetes & Endocrinology Internal Medicine news

Evaluating Sleep Optimization for Glycemic Control in Adults with Type 1 Diabetes: Insights from a Randomized Controlled Trial

By MedXY 07/03/2026

A 12-week randomized trial explored sleep optimization in adults with type 1 diabetes, revealing improved sleep quality and reduced diabetes distress but limited glycemic benefits except in patients with baseline A1C ≥7%.

Cardiology Diabetes & Endocrinology news

Ultra-Thin Sirolimus-Eluting Stents Show Noninferiority to Everolimus-Eluting Stents in Diabetic Multivessel CAD: Insights from TUXEDO-2 Trial

By MedXY 07/02/2026

The TUXEDO-2 trial demonstrated that ultra-thin strut biodegradable polymer sirolimus-eluting stents are noninferior to durable polymer everolimus-eluting stents in diabetic patients with multivessel coronary artery disease at 1-year follow-up.

Diabetes & Endocrinology Internal Medicine news

Enhancing Preventive Screening Uptake: EHR Portal Messages Boost Mammography Rates

By MedXY 07/02/2026

Iterative redesign of electronic health record (EHR) portal reminders significantly improved mammography screening adherence in an outpatient setting, demonstrating the value of concise messages with scheduling links, while retinal and HbA1c reminders showed no effect.

Diabetes & Endocrinology General Surgery news

Quantitative Autofluorescence Index Enhances Intraoperative Differentiation of Normal and Pathologic Parathyroid Glands

By MedXY 07/01/2026

Near-infrared autofluorescence heterogeneity measurement provides a real-time, quantitative tool during parathyroidectomy to distinguish hyperfunctional parathyroid glands from normal tissue, aiding surgical precision and potentially improving cure rates in hyperparathyroidism.

Diabetes & Endocrinology news Ophthalmology

Stimulating Thyrotropin Receptor Antibodies Amplify Fibroblast Expression of TSH and IGF-1 Receptors: Insights into Thyroid Eye Disease Pathogenesis

By MedXY 07/01/2026

Stimulating TSH receptor antibodies enhance expression of TSHR and IGF-1R in fibroblasts via receptor recycling, elucidating mechanisms underlying thyroid eye disease and identifying potential therapeutic targets.

Cardiology Diabetes & Endocrinology news

Continuous Glucose Monitoring-Derived Time in Range Predicts Longitudinal Changes in Arterial Stiffness in Type 2 Diabetes

By MedXY 07/01/2026

This study demonstrates that continuous glucose monitoring-derived time in range (TIR) is independently associated with progression of arterial stiffness in type 2 diabetes, highlighting TIR as a valuable metric beyond HbA1c for cardiovascular risk management.

Diabetes & Endocrinology Nephrology news

Continuous Glucose Monitoring and Survival Benefits in Diabetic Veterans on Dialysis: Insights from a Nationwide Cohort

By MedXY 07/01/2026

Among U.S. veterans with diabetes on dialysis, continuous glucose monitoring (CGM) use was associated with significantly lower mortality risk compared to non-CGM use, highlighting CGM's potential to improve survival in this high-risk population.