Highlights of the Research
The study demonstrates that preconception plasma trace metal levels in both partners significantly influence early IVF embryological outcomes. Key findings include:
- High exposure to trace metal mixtures in couples and male partners is associated with a decrease in best-quality embryos and blastocyst numbers.
- Specific individual elements show divergent effects: Iron (Fe), Lithium (Li), Strontium (Sr), and Molybdenum (Mo) are positively associated with favorable embryological outcomes.
- Conversely, Silver (Ag) and Thallium (Tl) were identified as harmful elements, negatively impacting fertilization and embryo development.
- The study underscores the necessity of a couple-based approach, rather than focusing solely on maternal health, to optimize assisted reproductive technology (ART) success.
