EMG-Guided Botulinum Toxin Injections Significantly Reduce Pain and Improve Sexual Function in Provoked Vestibulodynia

EMG-guided Onabotulinum toxin A (50U) significantly reduced pain Visual Analogue Scale (VAS) scores at 3 months compared to placebo (p=0.008).
Treatment led to sustained improvements in the Dermatology Life Quality Index (DLQI) at both 3-month and 6-month follow-ups.
Significant enhancements were observed in sexual desire and sexual satisfaction according to the Female Sexual Function Index (FSFI).
The study confirms that muscular dysfunction and hypertonicity are critical components of the pain profile in provoked vestibulodynia.

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