Moderate caffeinated coffee consumption (2 to 3 cups/day) was associated with an 18% reduction in incident dementia risk compared to non-consumers.
Similar neuroprotective benefits were observed for tea consumption (1 to 2 cups/day), while decaffeinated coffee showed no significant association with cognitive outcomes.
The study, spanning over 40 years of follow-up, also linked higher caffeine intake to lower prevalence of subjective cognitive decline and improved objective cognitive scores.
Dose-response analysis revealed a non-linear relationship, suggesting that moderate intake provides the most pronounced benefit for brain health.
