Micronutrient Supplementation Modulates Gut Microbiome in Children with ADHD: Insights from the MADDY Study

Highlight

  • Micronutrient supplementation leads to significant shifts in gut microbial diversity in children with ADHD.
  • Decreased abundance of phylum Actinobacteriota observed after micronutrient treatment compared to placebo.
  • Increased levels of butyrate-producing bacterial families Rikenellaceae and Oscillospiraceae correlate with clinical response.
  • Gut microbiota modulation may represent a mechanistic link between micronutrients and behavioral improvements in ADHD.

Study Background and Disease Burden

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