Maternal obesity metabolic phenotypes—metabolically healthy obesity (MHO) versus metabolically unhealthy obesity (MUO)—influence gestational weight gain (GWG), gestational diabetes incidence, and infant adiposity.
Despite intensive behavioral therapy (IBT) aiming to optimize GWG, no differential treatment response was observed between MHO and MUO groups in weight or adverse perinatal outcomes.
Maternal metabolic health status exerts a stronger effect on adverse outcomes than GWG alone, highlighting the need for early metabolic optimization during pregnancy.
