Highlight
– First-line IVF demonstrated a significantly higher cumulative live-birth rate compared to four cycles of IUI with ovarian stimulation in unexplained infertility.
– After extended treatment involving additional IVF cycles, cumulative live-birth rates between initial IUI and IVF groups were comparable.
– Serious adverse events were more common in the IVF group, largely related to oocyte retrieval and ovarian hyperstimulation.
– Results challenge current guidelines favoring IUI as the first-line therapy and inform patient-centered counseling regarding treatment choices.
Study Background
Specialty calculators
For clinical reference; use professional judgment.
