Highlights
- Systematic review and meta-analysis of 2,722 adults with malignant neoplasms shows intravenous vitamin C significantly prolongs overall survival compared to controls.
- Pooled median survival ratio for overall survival was 1.83 (95% CI: 1.40-2.40), indicating a nearly doubled median survival time.
- Progression-free survival showed a favorable trend but did not reach statistical significance.
- Subgroup analyses suggest benefits are more pronounced with lower vitamin C doses and in certain regional and combination therapy contexts.
Study Background and Disease Burden
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