### Patient Information A 9-year-old female patient presented with a longstanding history of atopic dermatitis (AD) characterized by severe eczematous lesions and pruritus from early childhood. Concurrently, she suffered from frequently relapsing steroid-sensitive nephrotic syndrome, diagnosed several years prior, with relapses increasing in frequency despite ongoing immunosuppressive treatment. Relevant medical history included multiple courses of systemic corticosteroids and tacrolimus. The patient’s family history was suggestive of atopic disorders but without known renal disease. ### Diagnosis On presentation, the patient exhibited active AD with widespread cutaneous lesions typical of severe disease. Laboratory investigations confirmed nephrotic syndrome characterized by significant proteinuria, hypoalbuminemia, hyperlipidemia, and edema during relapses. Histopathology from prior renal biopsy was consistent with minimal change disease, the most common cause…
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