Increased Risk of Pseudophakic Cystoid Macular Edema After Cataract Surgery in Eyes with Prior Pars Plana Vitrectomy: Insights from a Large Retrospective Cohort Study

Highlights

• Prior pars plana vitrectomy (PPV) is independently associated with a higher incidence of pseudophakic cystoid macular edema (CME) after cataract surgery.
• Risk of CME was approximately 3.7 times greater in eyes with prior PPV compared to non-vitrectomized eyes.
• This elevated risk persists across indications for vitrectomy, including retinal detachment and non-retinal detachment cases.
• Findings emphasize the need for vigilance in postoperative monitoring and consideration of prophylactic strategies in vitrectomized eyes undergoing cataract extraction.

Study Background and Disease Burden