Differential Physical Activity Responses to Diabetes Risk Reduction Interventions According to Prediabetes Phenotype: Insights from Pooled Randomized Controlled Trials

Highlights

  • Lifestyle interventions increase physical activity and reduce diabetes risk variably across prediabetes phenotypes.
  • Individuals with impaired glucose tolerance and combined IFG+IGT show greater physical activity gains than those with isolated IFG.
  • Structured group-based interventions with goal setting effectively enhance step counts, particularly in IGT and IFG+IGT groups.
  • Emerging digital and AI-driven interventions provide scalable alternatives with comparable efficacy in improving activity and metabolic outcomes.

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