Global Patterns and Challenges of Antibiotic Prescribing in Primary Care: A Comprehensive Systematic Review and Meta-Analysis

Highlights

  • A global meta-analysis encompassing 174 studies from 51 countries found that 42.1% of primary care prescriptions include antibiotics.
  • Inappropriate antibiotic prescribing is prevalent, constituting 57.6% of all antibiotic prescriptions in primary care.
  • Higher antibiotic prescribing rates are observed in lower-middle-income and low-income countries, with rural areas showing greater prevalence than urban areas.
  • No significant reduction in antibiotic prescribing was observed over the past two decades, underscoring the need to re-evaluate antimicrobial stewardship strategies globally.

Background

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