antimicrobial stewardship

Daily Chlorhexidine Bathing in the ICU: Re-evaluating Infection Prevention and Antimicrobial Stewardship through the CLEAN-IT Trial

By MedXY 03/02/2026

This review synthesizes findings from the CLEAN-IT trial and historical data to evaluate the impact of chlorhexidine bathing on nosocomial infections, MDR pathogens, and reserve antibiotic consumption in critically ill patients.

AI Infectious Diseases news

AI-Driven Decision Support for Antibiotic Switching: Why Clinicians Value Caution Over Speed

By MedXY 01/15/2026

A randomized multimethod study reveals that while AI clinical decision support systems for antibiotic switching are well-received, their primary influence is reinforcing conservative prescribing. The study underscores that usability and clinical evidence outweigh the importance of AI explanations at the point of care.

Critical Care Infectious Diseases news

Precision Dosing in the ICU: Extended Infusions of Meropenem and Piperacillin Optimize Therapy During Renal Replacement

By MedXY 12/28/2025

A large-scale multinational study reveals that meropenem and piperacillin dosing during renal replacement therapy must be tailored to RRT intensity and urine output, with extended infusions significantly improving therapeutic target attainment.

news Public Health Specialties

Global Patterns and Challenges of Antibiotic Prescribing in Primary Care: A Comprehensive Systematic Review and Meta-Analysis

By MedXY 08/21/2025

A global meta-analysis reveals that over 40% of primary care prescriptions contain antibiotics, with more than half being inappropriate, highlighting urgent needs for improved antimicrobial stewardship worldwide.

Clinical Updates Infectious Diseases news Specialties Urology

Individualised Versus Standard 10-Day Antibiotic Therapy in Pediatric Febrile UTI: Insights from the INDI-UTI Trial

By MedXY 08/02/2025

A Danish multicentre trial found individualised, shorter antibiotic regimens for febrile pediatric UTIs reduce overall antibiotic exposure and adverse events, but with a modestly higher recurrence risk compared to standard 10-day treatment.