Early TAVR Benefits in Asymptomatic Severe Aortic Stenosis: Insights from Cardiac Biomarker Analysis in the EARLY TAVR Trial

Highlight

– Early TAVR intervention outperforms surveillance even in asymptomatic severe aortic stenosis patients.
– Elevated NT-proBNP and hs-cTnT levels correlate with higher adverse event rates.
– Contrary to expectations, patients with lower baseline hs-cTnT benefit more from early TAVR.
– Single biomarker measurements have limited utility in timing TAVR for asymptomatic patients.

Study Background and Disease Burden