Highlight
1. This nationwide Dutch cohort study found that 90% of patients diagnosed with Barrett’s esophagus (BE)-related dysplasia or esophageal adenocarcinoma (EAC) had not undergone prior endoscopic surveillance.
2. Patients without prior surveillance presented predominantly with advanced stage (≥II) disease, underscoring late detection.
3. Among patients with prior surveillance, the incidence of missed advanced neoplasia was low, suggesting effective surveillance when conducted.
4. The findings emphasize an urgent need for targeted, evidence-based screening and surveillance strategies to improve early diagnosis and optimize patient outcomes.
