Delayed Remote Ischemic Preconditioning Reduces Contrast-Associated Acute Kidney Injury After Coronary Angiography and PCI: Insights from a Randomized Trial

Delayed remote ischemic preconditioning (RIPC) 24 hours before coronary angiography or PCI significantly reduces contrast-associated acute kidney injury (CA-AKI) incidence in at-risk patients.
RIPC delivers four cycles of 5-minute ischemia via upper arm cuff inflation, offering a non-invasive kidney-protective strategy.
No significant differences were observed in secondary outcomes such as renal replacement therapy and mortality, warranting larger studies.
This approach could alter pre-procedural preventive strategies for patients at risk of CA-AKI.