Highlight
– Dapagliflozin treatment improved MASH activity scores and fibrosis outcomes significantly compared to placebo.
– MASH resolution without fibrosis worsening was nearly threefold higher in the dapagliflozin group.
– Fibrosis improvement occurred in 45% of treated patients without increased adverse events.
– The treatment was well tolerated, with very low rates of discontinuation due to adverse events.
Study Background and Disease Burden
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