Blackcurrant Anthocyanins Improve Post‑prandial Vascular Function and Platelet Reactivity — Acute RCT Insights and Clinical Implications

Highlights

– In a randomized, double‑blind crossover trial (n=23), a 200‑mL blackcurrant beverage delivering 711 mg anthocyanins produced a cumulative improvement in brachial artery flow‑mediated dilation (FMD) over 6 h after a high‑fat meal versus a matched placebo (iAUC difference 5.75 ± 1.32; P=0.014).

– The intervention reduced ex vivo ADP‑ and collagen‑induced platelet aggregation across the postprandial period (substantial iAUC reductions; P<0.01), and blunted a postprandial rise in plasma IL‑8 (iAUC difference −1826.8 ± 618.6; P=0.015, exploratory).

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