Highlights
– A 60‑day, double‑blind RCT (n=60) tested a combined supplement containing riceberry anthocyanin (≈0.28 g/day) + inulin (Jerusalem artichoke) and rice bran (≈1.26 g/day each; total dose ≈2.8 g/day) vs. maltodextrin placebo.
– The supplement group showed statistically and clinically meaningful reductions in fasting plasma glucose (mean fall ≈45 mg/dL; interaction p=0.03), HbA1c (−0.7% absolute; interaction p=0.002) and LDL‑C (−14 mg/dL; interaction p=0.02). No safety signals were observed.
– Markers of oxidative stress (MDA), vitamin C, hsCRP and cardiorespiratory fitness did not change significantly; mechanisms remain speculative and require mechanistic studies.
