Adversity Across the Lifespan: The Compounding Impact of Childhood and Adult Stress on Dementia and Stroke Risk

Highlights

Exposure to adverse childhood experiences (ACEs) and adverse adulthood experiences (AAEs) is significantly associated with an increased risk of incident dementia and stroke in middle-aged and older adults.

Participants in high-risk groups for both ACEs and AAEs exhibited a more than three-fold increase in dementia risk and a 2.5-fold increase in stroke risk compared to those with low exposure.

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