Highlight
- Serum plasmalogen levels and gut microbiota profiles strongly associate with seizure reduction in children with drug-resistant epilepsy on the ketogenic diet.
- Positive correlation of anti-seizure effect with Faecalibacterium prausnitzii, Alistipes spp., and Christensenella minuta; negative correlation with Escherichia coli strains.
- Potential for targeted microbiome or metabolite therapies to enhance seizure control.
Study Background and Disease Burden
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