Serum plasmalogen levels and gut microbiota profiles strongly associate with seizure reduction in children with drug-resistant epilepsy on the ketogenic diet.
Positive correlation of anti-seizure effect with Faecalibacterium prausnitzii, Alistipes spp., and Christensenella minuta; negative correlation with Escherichia coli strains.
Potential for targeted microbiome or metabolite therapies to enhance seizure control.
