Posted inCardiology Neurology news
DKK2 Inhibition: A Novel Neurovascular Strategy to Salvage the Ischaemic Penumbra and Protect the Blood-Brain Barrier
New research published in the European Heart Journal identifies Dickkopf-related protein 2 (DKK2) as a primary driver of neurovascular injury post-stroke. By suppressing Wnt signalling, DKK2 exacerbates neuronal death and blood-brain barrier breakdown, marking it as a high-priority therapeutic target.