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Preserved Copeptin Kinetics with Aging: Insights into Water Homeostasis and Hyponatremia Risk in Older Adults
Posted inDiabetes & Endocrinology Internal Medicine news

Preserved Copeptin Kinetics with Aging: Insights into Water Homeostasis and Hyponatremia Risk in Older Adults

Posted by By MedXY 08/17/2026
This study reveals that copeptin kinetics remain mostly intact in healthy aging, but older adults exhibit diminished copeptin suppression after hydration, potentially explaining their increased vulnerability to hyponatremia.
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Ultra-Early Versus Early Vasopressin Initiation After Norepinephrine Escalation in Septic Shock: Insights from a Target Trial Emulation
Posted inCritical Care Internal Medicine news

Ultra-Early Versus Early Vasopressin Initiation After Norepinephrine Escalation in Septic Shock: Insights from a Target Trial Emulation

Posted by By MedXY 08/12/2026
This study emulated a target trial to compare ultra-early (0-3h) versus early (>3-6h) vasopressin initiation after norepinephrine escalation in septic shock, revealing significant mortality and renal therapy benefits with ultra-early use.
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