TNM staging – Medxy AI

Imaging-Detected Extranodal Extension in p16-Positive Oropharyngeal Cancer: Insights from the RTOG 1016 Study

By MedXY 08/31/2026

This analysis of RTOG 1016 validates the prognostic value of imaging-detected extranodal extension (iENE) in p16-positive oropharyngeal cancer, supporting its integration into the AJCC/UICC TNM9 staging system and its implications for patient risk stratification and management.

news Oncology Otorhinolaryngology

Optimizing Prognosis: The New AJCC Version 9 Staging for Salivary Gland Carcinoma

By MedXY 02/20/2026

The proposed AJCC/UICC Version 9 staging for salivary gland carcinoma shifts toward a unified, specific system using lymph node count and extranodal extension, significantly improving prognostic accuracy for both major and minor salivary gland malignancies.

Oncology Otorhinolaryngology Specialties

Revising the TNM Classification for HPV-Associated Oropharyngeal Carcinoma: Improving Prognostic Stratification with Imaging-Detected Extranodal Extension

By MedXY 10/22/2025

A new clinical TNM staging proposal incorporating imaging-detected extranodal extension (iENE) refines prognostic accuracy in HPV-positive oropharyngeal carcinoma, aiding risk stratification and future treatment strategies.