Predicting Walking Ability in Nontraumatic Spinal Cord Injury Using Machine Learning: A Novel Temporal Validation Study

Highlight

  • Development of a Gradient Boosting Decision Tree-based model to predict walking ability in patients with nontraumatic spinal cord injury (NTSCI) using admission clinical data.
  • The model demonstrated strong performance (AUC 0.91, recall 0.92) on internal testing and maintained promising accuracy (0.81) in a temporal external validation cohort.
  • Key predictive features included total lower limb muscle strength and patient age, highlighting important clinical factors for prognosis.
  • Findings are preliminary; external multicenter validation and larger sample sizes are needed before clinical integration.

Study Background

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