stem cell therapy

Stem Cell Therapy for Complex Perianal Fistulas: Why the ADMIRE CD II Trial Missed Its Mark

By MedXY 03/06/2026

The ADMIRE CD II Phase 3 trial failed to show a significant benefit of darvadstrocel over placebo for complex perianal fistulas in Crohn's disease, primarily due to an unexpectedly high remission rate in the placebo-controlled surgical arm.

news Pediatrics

Cellular Therapy for In-Utero Myelomeningocele Repair: Results from the CuRe Phase 1 Trial

By MedXY 03/06/2026

This phase 1 study evaluates the safety of placenta-derived mesenchymal stem cells (PMSCs) seeded on an extracellular matrix for in-utero repair of myelomeningocele, demonstrating successful surgical outcomes and no cell-related adverse events in six patients.

news Orthopedics

Stem Cell Therapy for Avascular Necrosis of the Femoral Head: Promise or Pitfall? A Comprehensive Meta-Analysis

By MedXY 10/12/2025

This meta-analysis evaluates stem cell therapy combined with mechanical support for avascular necrosis of the femoral head, highlighting modest improvements in function and delayed disease progression compared to stem cells alone.

Diabetes & Endocrinology Specialties Transplantation

Advancing Type 1 Diabetes Care: Stem Cell-Derived Islet Therapy with Zimislecel

By MedXY 09/10/2025

Zimislecel, an allogeneic stem cell-derived islet-cell therapy, demonstrates promising safety and efficacy for type 1 diabetes, restoring physiologic islet function and enabling insulin independence in a phase 1-2 trial.

Clinical Updates Neurology news Pediatrics Specialties

Intrathecal Autologous Bone Marrow Mononuclear Cell Therapy Plus Education: A Promising Approach for Autism Spectrum Disorder?

By MedXY 08/08/2025

A phase II trial finds that intrathecal autologous bone marrow mononuclear cell therapy combined with education significantly improves core symptoms and adaptive behaviors in young children with ASD compared to education alone.

news OB/GYN & Women's Health Specialties

Stem Cell Therapy: A New Frontier in Restoring Fertility for Women with Ovarian Failure

By MedXY 07/29/2025

Recent research highlights stem cell therapy as a promising method for improving fertility in women facing ovarian failure, showing significant oocyte activation and pregnancy rates.