status epilepticus

Optimizing Etiologic Investigations After Status Epilepticus: Diagnostic Yield and Therapeutic Implications from the ICTAL Registry

By MedXY 09/23/2026

Etiologic investigations after status epilepticus (SE) demonstrate variable diagnostic yield and significantly influence treatment decisions, especially when guided by clinical pretest probability. Tailored diagnostic strategies enhance timely and targeted interventions in SE management.

$Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus$

Critical Care Neurology news

Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus

By MedXY 06/10/2026

This study found that cryptogenic NORSE causes severe, rapidly rising neuroaxonal injury, measured by NfL, and that higher NfL predicts worse short-term outcome. S100B was not useful for distinguishing groups.

Neurology news Public Health

Status Epilepticus Mortality in U.S. Adults Is Rising, With the Highest Burden in Older Adults, Men, Non-Hispanic Black Populations, and the South

By MedXY 05/03/2026

A U.S. mortality analysis from 1999 to 2020 found increasing deaths from status epilepticus after 2007, with marked disparities by age, sex, race/ethnicity, and region.

$Neurofilament Light Chain Reveals Rapid Neuroaxonal Injury in New-Onset Refractory Status Epilepticus$

Critical Care Neurology news

Neurofilament Light Chain Reveals Rapid Neuroaxonal Injury in New-Onset Refractory Status Epilepticus

By MedXY 04/30/2026

In a multinational cross-sectional study, serum and CSF neurofilament light chain—unlike S100B—tracked severe acute brain injury in cryptogenic NORSE, rose rapidly over the first 3 weeks, and predicted poor short-term outcome, supporting urgent neuroprotective treatment.