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Right Ventricular Failure

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Unraveling Right Ventricular Failure in PH-HFpEF: Integrative Insights from Vascular Mechanics and Transcriptomics
Posted inCardiology news

Unraveling Right Ventricular Failure in PH-HFpEF: Integrative Insights from Vascular Mechanics and Transcriptomics

Posted by By MedXY 08/25/2026
This study integrates vascular mechanics, advanced imaging, and myocardial transcriptomics to elucidate the mechanisms of right ventricular failure in pulmonary hypertension secondary to heart failure with preserved ejection fraction, uncovering key vascular and molecular remodeling pathways.
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From Compensation to Collapse: How Cardiac Myofibroblasts and UCP2 Genetic Variants Dictate Right Ventricular Fate in PAH
Posted inCardiology news Respiratory

From Compensation to Collapse: How Cardiac Myofibroblasts and UCP2 Genetic Variants Dictate Right Ventricular Fate in PAH

Posted by By MedXY 03/09/2026
This study identifies the transition of cardiac fibroblasts to myofibroblasts as a critical driver of right ventricular failure in PAH, highlighting the role of UCP2 deficiency and the rs659366 SNP as key clinical indicators of decompensation.
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