non-relapse mortality

Real-World Incidence, Risk Factors, and Biomarker Validation for SOS/VOD After Allogeneic HSCT in Adults: Insights from the Spanish GETH-TC Registry

By MedXY 08/12/2026

A comprehensive retrospective analysis of 793 adult allo-HSCT cases identifies key clinical risk factors and validates the EASIX score as a predictive biomarker for SOS/VOD, highlighting the syndrome's significant impact on non-relapse mortality.

Hematology-Oncology news

CHIME: A Novel HLA Eplet Model Predicting Non-Relapse Mortality in Haploidentical Hematopoietic Cell Transplantation

By MedXY 07/09/2026

This study introduces CHIME, a novel HLA eplet mismatch model, revealing its association with non-relapse mortality and severe aGvHD in haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide, improving outcome prediction over traditional allele mismatch methods.

Hematology-Oncology news Oncology

Frontline Allogeneic Transplantation Outperforms Pretransplant IPSS-M Downstaging in Myelodysplastic Neoplasms

By MedXY 05/21/2026

In adults with myelodysplastic neoplasms undergoing allogeneic transplantation, pretransplant cytoreduction modestly improved IPSS-M in some patients but did not improve post-transplant survival and was associated with higher non-relapse mortality.