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Mosaicism

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New Consensus on APC Mosaicism: Transforming the Diagnosis and Management of Unexplained Polyposis
Posted inGastroenterology news Oncology

New Consensus on APC Mosaicism: Transforming the Diagnosis and Management of Unexplained Polyposis

Posted by By MedXY 03/09/2026
A landmark study in Gastroenterology reveals that APC mosaicism accounts for nearly 10% of unexplained colorectal polyposis. New guidelines recommend specific testing thresholds and surveillance strategies to prevent colorectal cancer in these high-risk patients.
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Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes
Posted innews OB/GYN & Women's Health

Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes

Posted by By MedXY 12/24/2025
A large, double-blinded study reveals that reporting embryo mosaicism (ICN) during PGT-A provides no meaningful clinical predictive value for live birth rates, suggesting that current classification systems may unnecessarily limit embryo selection without improving overall success in routine IVF practice.
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