intensive care – Medxy AI

Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT

By MedXY 09/03/2026

A pilot randomized trial comparing targeted temperature management at 35°C versus normothermia in intubated heatstroke patients showed no survival or neurological benefit from hypothermia but increased gastrointestinal injury and arrhythmias, highlighting safety concerns and questioning routine hypothermia use in this setting.

Critical Care Gastroenterology news

The Microbiome in Critical Illness: Transforming ICU Care Through Microbial Insights

By MedXY 08/28/2026

This review explores how the human microbiome influences management and outcomes in critically ill patients, emphasizing gastrointestinal microbial dynamics, disruption by critical illness and therapies, and emerging interventions to restore microbial homeostasis in the ICU.

Critical Care Internal Medicine news

Post-ICU Frailty in Older Adults Following Septic Shock: Key Predictors and Clinical Implications

By MedXY 08/26/2026

This study identifies baseline frailty, organ dysfunction severity, and corticosteroid use as independent predictors of severe post-intensive care frailty in older septic shock survivors, highlighting critical factors for targeted post-ICU care.

Anesthesiology Critical Care news

Dexmedetomidine Reduces Agitation and Accelerates Recovery in Non-Intubated ICU Patients with Hyperactive Delirium: Insights from the 4D Trial

By MedXY 12/26/2025

The 4D randomized clinical trial demonstrates that dexmedetomidine significantly reduces agitation duration and improves clinical outcomes in non-intubated ICU patients with hyperactive delirium, providing a safe and effective alternative to standard care without increasing the need for mechanical ventilation.

Anesthesiology Critical Care news

Dexmedetomidine for Analgesia in Nonintubated Patients With Traumatic Rib Fractures: A Randomized Clinical Trial Analysis

By MedXY 10/10/2025

This trial found that adjunctive dexmedetomidine did not reduce opioid use, pain scores, or pulmonary complications in nonintubated ICU patients with traumatic rib fractures, challenging its routine analgesic use in this setting.

Neurology news Specialties

Long-Term Outcomes in Critically Ill Adults With Acute Encephalitis: Insights From a Multicenter French Cohort

By MedXY 09/23/2025

A prospective study of 310 ICU patients with acute encephalitis reveals that half suffer moderate to severe disability or death at 3 months. Autoimmune encephalitis patients show notable recovery over one year, highlighting the need for tailored long-term support.