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doxorubicin cardiotoxicity

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MODICA: A Mitochondrial Peptide Shielding the Heart Against Doxorubicin-Induced Cardiotoxicity
Posted inCardiology news Oncology Specialties

MODICA: A Mitochondrial Peptide Shielding the Heart Against Doxorubicin-Induced Cardiotoxicity

Posted by MedXY By MedXY 09/06/2025
MODICA, a mitochondrial sORF-encoded peptide, protects cardiac function from doxorubicin toxicity by inhibiting VDAC oligomerization, reducing apoptosis and fibrosis, highlighting a novel cardioprotective therapeutic target.
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