Confocal Laser Endomicroscopy-Guided Exclusion Diet Fails to Improve IBS Symptoms in Controlled Trial

Confocal Laser Endomicroscopy-Guided Exclusion Diet Fails to Improve IBS Symptoms in Controlled Trial

A randomized controlled crossover trial found that individualized exclusion diets based on confocal laser endomicroscopy (CLE) findings do not significantly improve symptoms in irritable bowel syndrome (IBS) patients compared to sham diets. Moreover, CLE-detected mucosal alterations are non-specific and present in healthy individuals.
Dynamic Effects of Short-Term Dietary Energy Loads on Fecal Serotonin, Gut Microbiome Tryptophanase, and Energy Absorption: Insights from a Randomized Crossover Trial

Dynamic Effects of Short-Term Dietary Energy Loads on Fecal Serotonin, Gut Microbiome Tryptophanase, and Energy Absorption: Insights from a Randomized Crossover Trial

Short-term alterations in dietary energy intake significantly impact fecal serotonin, gut microbiome tryptophanase activity, and energy absorption, highlighting a complex interaction that may influence metabolic health.