Thiết kế Thử nghiệm Lâm sàng

Designing Cardiovascular Outcomes Trials in Clonal Hematopoiesis: A Precision Medicine Imperative

By MedXY 09/14/2026

Clonal hematopoiesis of indeterminate potential (CHIP) poses a novel cardiovascular risk. This article explores challenges and strategies for designing cardiovascular outcomes trials tailored to CHIP’s genetic heterogeneity and clinical complexity.

news Oncology

Divergent Roles of Federal and Industry Sponsors in US Cancer Clinical Trials: Insights from 2008 to 2024

By MedXY 08/22/2026

This study quantifies how federal and industry sponsorship differ in US cancer clinical trials, highlighting complementary focuses: industry emphasizes single-agent drug therapies, while federal trials prioritize multimodality regimens, rare cancers, pediatric populations, and supportive care.

Clinical Updates news Ophthalmology Public Health

Optimizing Geographic Atrophy Clinical Trial Design: The Role of Run-In Phases, Single-Arm Architectures, and Functional Endpoints

By MedXY 05/18/2026

This review synthesizes evidence on improving geographic atrophy trial efficiency through innovative run-in phases, single-arm designs, and superior functional biomarkers like microperimetry to reduce required sample sizes.