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Adjunct Intra-arterial Alteplase After Successful Basilar Thrombectomy Was Safe but Did Not Improve 90-Day Outcomes in IAT-TOP

By MedXY 05/10/2026

In the IAT-TOP randomized trial, intra-arterial alteplase after successful EVT for acute basilar artery occlusion did not improve 90-day functional independence, while symptomatic intracranial hemorrhage and mortality were similar between groups.

Neurology news

Tenecteplase Improves 90-Day Functional Outcomes in Basilar Artery Occlusion Within a 24-Hour Window: Results from TRACE-5

By MedXY 02/16/2026

The TRACE-5 trial demonstrates that tenecteplase significantly improves functional outcomes for patients with basilar artery occlusion within 24 hours of onset, offering a safe and effective extension of the therapeutic window for this high-mortality condition.

Neurology news

Thrombectomy for Basilar Artery Occlusion: Sustained Efficacy and Survival Gains at Three Years

By MedXY 01/02/2026

The 3-year outcomes of the ATTENTION trial confirm that endovascular thrombectomy for acute basilar artery occlusion provides durable functional benefits and significantly reduces mortality compared to medical management, establishing its long-term superiority as the standard of care for younger and middle-aged patients.