alcohol-associated liver disease

KIF13B-KPNA2-PPARα Axis: A Novel Target for Mitigating Alcohol-Associated Liver Steatosis

By MedXY 08/22/2026

Emerging evidence identifies KIF13B facilitating KPNA2-mediated nuclear import of PPARα as a critical mechanism to mitigate alcohol-associated liver steatosis, highlighting novel therapeutic strategies for ALD.

Clinical Updates Gastroenterology news

Uncovering the Hepatocyte CEBPA-ORM1 Axis: A Novel Regulatory Pathway and Biomarker in Alcohol-Associated Liver Disease

By MedXY 03/10/2026

This review synthesizes recent findings identifying the CEBPA-ORM1 axis as a critical suppressor of alcohol-associated liver disease, highlighting its potential as both a therapeutic target and a diagnostic biomarker for disease staging.

Gastroenterology news Public Health

Cutting the Curve: Consensus Strategies to Reduce Alcohol‑Associated Liver Disease in the Population

By MedXY 11/09/2025

A concise synthesis of a 2025 multistakeholder Lancet workshop consensus on population and clinical strategies to prevent, detect, and manage alcohol‑associated liver disease.