Gastroenterology – Page 16

Early Control of Ulcerative Colitis and Its Impact on Long-Term Outcomes: Insights from the UNIFI Phase 3 Study

By MedXY 08/26/2025

Achieving disease clearance early after induction therapy with ustekinumab in ulcerative colitis patients predicts sustained clinical remission, symptom control, and improved quality of life over four years.

Clinical Updates Gastroenterology news Oncology Specialties

Pathobionts in Colorectal Tumour Microbiota: Predicting Survival and Shaping Oncological Outcomes

By MedXY 08/24/2025

This study identifies specific pathobiont bacterial clusters in colorectal tumour microbiota that predict disease-free survival post-surgical resection, linking microbial and metabolic profiles to colorectal cancer prognosis.

Clinical Updates Family Medicine & Nutrition Gastroenterology news Specialties

Silymarin in Clinical Medicine: A Decade of Therapeutic Advances and Future Disease Targets

By MedXY 08/24/2025

Comprehensive review of recent decade research on silymarin elucidates its antioxidant, anti-inflammatory, and hepatoprotective effects, highlighting promising clinical applications in metabolic diseases, neurodegeneration, liver disorders, and inflammatory conditions, with emerging potential in oncology and dermatology.

Clinical Updates Diabetes & Endocrinology Gastroenterology news Specialties

HTD1801 Shows Promising Histologic Improvement in Metabolic Dysfunction-Associated Steatohepatitis: Insights from Preclinical and Phase 2 Clinical Studies

By MedXY 08/24/2025

HTD1801 (berberine ursodeoxycholate) significantly improves liver histology and reduces fibrosis in metabolic dysfunction-associated steatohepatitis (MASH) as demonstrated by preclinical models and a Phase 2 trial.

Family Medicine & Nutrition Gastroenterology Medical News news Specialties

Daily Coffee: A Natural Ally Against Liver Damage? Exploring the Science Behind the Buzz

By MedXY 08/23/2025

Emerging research suggests that drinking a daily cup of coffee could reduce the risk of liver damage by up to 30%, offering new hope in liver health management.

Family Medicine & Nutrition Gastroenterology Medical News news Specialties

Understanding Intestinal Polyps: When Should They Be Removed?

By MedXY 08/23/2025

Intestinal polyps are common findings during colonoscopy, especially among those older than 50. While most are benign, certain types carry a significant risk of progressing to colorectal cancer. This article explores polyp types, risk factors, and clinical recommendations for removal.

Clinical Updates Gastroenterology Specialties

Berberine Demonstrates Long-Term Prevention of Colorectal Adenoma Recurrence: A Six-Year Follow-Up Study

By MedXY 08/23/2025

Berberine shows sustained efficacy and safety in reducing colorectal adenoma recurrence and neoplasm occurrence after polypectomy, providing new directions for secondary prevention of colorectal cancer.

Clinical Updates Family Medicine & Nutrition Gastroenterology news Oncology Specialties

Butyrate-Producing Clostridium butyricum: A Direct Interactor with Colorectal Cancer Cells that Reverses Immune Suppression and Enhances Checkpoint Inhibitor Efficacy

By MedXY 08/23/2025

Recent research uncovers that the probiotic Clostridium butyricum directly interacts with colorectal cancer cells to inhibit immune suppression via the secD-GRP78 axis, restoring CD8+ T cell antitumor function and enhancing PD-1 inhibitor therapy.

Critical Care Gastroenterology Specialties

Antibiotic Exposure as a Major Risk Factor for Clostridioides difficile Infection: Evidence from a Large Israeli Cohort and Systematic Reviews

By MedXY 08/21/2025

Recent research confirms that antibiotic exposure doubles the risk of hospital-onset Clostridioides difficile infection (CDI), especially in non-carriers, underscoring the central role of antibiotic stewardship and the need for additional preventive strategies in asymptomatic carriers.

Family Medicine & Nutrition Gastroenterology news Oncology Specialties

Anti-Inflammatory Dietary Education Reduces Frailty in Colorectal Cancer Patients: Insights from a 12-Week Randomized Controlled Trial

By MedXY 08/18/2025

A 12-week anti-inflammatory dietary education significantly improved frailty, nutritional status, inflammatory biomarkers, and quality of life in frail colorectal cancer patients undergoing chemotherapy.

$Cyclosporin Therapy: A Promising Rescue Treatment for Severe Steroid-Refractory Ulcerative Colitis$

Gastroenterology Specialties

Cyclosporin Therapy: A Promising Rescue Treatment for Severe Steroid-Refractory Ulcerative Colitis

By MedXY 08/17/2025

Cyclosporin demonstrated high clinical response rates in adults with severe steroid-refractory ulcerative colitis, allowing over half to avoid colectomy and highlighting its role as an effective rescue therapy.

Gastroenterology General Surgery news Specialties

Five-Year Outcomes of Per-Oral Endoscopic Myotomy vs. Laparoscopic Heller’s Myotomy Plus Dor Fundoplication in Idiopathic Achalasia

By MedXY 08/14/2025

A multicenter randomized trial shows POEM is non-inferior to LHM plus Dor fundoplication for achalasia symptom control at 5 years, with differing reflux profiles.

Gastroenterology news Specialties

Durable Remission and Safety of Upadacitinib in Moderate to Severe Ulcerative Colitis: Insights from the Phase 3 U-ACTIVATE Long-Term Extension Interim Analysis

By MedXY 08/14/2025

Interim data from the U-ACTIVATE study demonstrate sustained clinical and endoscopic remission and a consistent safety profile for upadacitinib up to 3 years in moderate to severe ulcerative colitis.

Gastroenterology General Surgery news Specialties

Endoscopic Ultrasound-Guided Gastroenterostomy Reduces Reintervention in Malignant Gastric Outlet Obstruction: Insights from the Multicentre DRA-GOO Trial

By MedXY 08/14/2025

A multicentre RCT demonstrated that endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) significantly lowers 6-month reintervention rates and improves gastric outlet obstruction symptoms compared to duodenal stenting in unresectable malignant gastric outlet obstruction.

Clinical Updates Gastroenterology news Specialties

Etrasimod in the Management of Eosinophilic Oesophagitis: Promising Results from the VOYAGE Phase 2 Trial

By MedXY 08/14/2025

The VOYAGE phase 2 trial demonstrated that etrasimod, an oral S1P receptor modulator, significantly reduces oesophageal eosinophilic inflammation and improves endoscopic findings in adults with eosinophilic oesophagitis, with a favorable safety profile over 52 weeks.

Family Medicine & Nutrition Gastroenterology news Specialties

Examining the Role of Gluten and Wheat in Irritable Bowel Syndrome: Insights from a Double-Blind, Sham-Controlled Crossover Trial

By MedXY 08/14/2025

A rigorous trial reveals that perceived symptom worsening from gluten or wheat in IBS patients may largely be driven by expectation rather than the substances themselves, underscoring the importance of distinguishing true sensitivities from placebo effects.

Gastroenterology General Surgery news Specialties

Appendicectomy Plus Medical Therapy Significantly Reduces Relapse in Ulcerative Colitis: Insights from the ACCURE Trial

By MedXY 08/14/2025

The ACCURE trial demonstrates that laparoscopic appendicectomy combined with standard medical therapy significantly lowers 1-year relapse rates compared to medical therapy alone in ulcerative colitis patients in remission.

AI Gastroenterology news Specialties

AI in Colonoscopy: Enhancing Detection or Eroding Physician Skills?

By MedXY 08/13/2025

The integration of AI in colonoscopy improves adenoma detection but raises concerns about declining physician skills when AI support is withdrawn, highlighting a potential clinical 'de-skilling' effect.

Clinical Updates Diabetes & Endocrinology Gastroenterology news Specialties

Dapagliflozin Shows Promising Benefits for Patients with Metabolic Dysfunction-Associated Steatohepatitis (MASH): A Landmark Multicentre Trial

By MedXY 08/13/2025

Dapagliflozin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis outcomes without increasing adverse events, according to a rigorous 48-week randomized trial.

Gastroenterology news Oncology Specialties

Four Typical Early Signs of Colorectal Cancer: What to Watch For

By MedXY 08/10/2025

Colorectal cancer often shows subtle bowel changes early. Know the four warning signs—diarrhea, constipation, altered stool shape, and rectal bleeding—and when to seek screening and treatment.