Highlight
– Hormone therapy in young women with locally advanced cervical cancer treated by chemoradiotherapy reduces long-term risks of type 2 diabetes, cerebrovascular events, and skeletal fractures.
– No increased incidence of thromboembolism, breast cancer, or colorectal cancer was observed with hormone therapy.
– Hormone therapy was associated with improved overall survival during a median follow-up exceeding 11 years.
– These findings suggest hormone therapy is a safe and beneficial intervention in this undertreated population at risk of premature menopause.
