Targeted hypothermia at 33°C does not improve functional outcomes or societal participation at 24 months compared to targeted normothermia with early fever management.
Cognitive outcomes, measured by MoCA and SDMT, showed no significant difference between the two temperature strategies in the long term.
The majority of functional recovery occurs within the first six months post-arrest, followed by a general plateau in the overall population.
Despite the population-level plateau, significant intraindividual variability exists, with some patients continuing to improve or decline up to two years later.
The Evolution of Temperature Management in Post-Cardiac Arrest Care