Racial and Ethnic Disparities in Treatment Initiation and Survival Among Patients With Endometrial Cancer: Socioeconomic Modifiers and Clinical Implications

Highlights

• Persistent racial and ethnic disparities are evident in treatment initiation delays and survival outcomes among women with advanced endometrial cancer.
• Socioeconomic status (SES) significantly modifies these disparities, with low SES exacerbating delays in treatment particularly among non-Hispanic Black and Hispanic/Latina women.
• An inverse SES effect was observed whereby non-Hispanic Black women in high SES areas exhibited higher all-cause mortality despite adjusting for clinical factors.
• Social determinants of health play a critical role, indicating the need for multifaceted interventions addressing both clinical and socioeconomic barriers.