Personalizing Allogeneic Hematopoietic Cell Transplantation in Adult AML Using Measurable Residual Disease Testing

Highlight

  • MRD testing stratifies AML patients in remission by relapse risk post-allogeneic HCT.
  • MRD guides decisions on transplantation eligibility, conditioning regimen intensity, and post-transplant surveillance.
  • Emerging MRD-based interventions include post-transplant maintenance and pre-emptive therapy to reduce relapse.
  • Clinicians face challenges interpreting MRD results amid evolving methodologies and incomplete standardization.

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