Highlights
- Neuropsychiatric symptoms, even in the absence of cognitive impairment, are linked to deteriorated daily functioning in older adults.
- Decreased motivation and emotional dysregulation are the strongest predictors of difficulties in daily activities.
- Apathy and depression further affect the ability to initiate and perform complex daily tasks.
- Partner-reported assessments may be more sensitive in detecting functional decline related to behavioral symptoms.
Clinical Background and Disease Burden