Autistic transgender and gender diverse (TGD) adults report more challenges in adhering to gender-affirming hormone therapy (GAHT) compared to their non-autistic peers.
Key barriers include sensory processing differences and executive functioning difficulties, affecting medication administration and tolerability.
Successful adherence strategies involve developing consistent routines, integrating GAHT into personal care, leveraging peer support, and involving trusted individuals in care appointments.
This evidence underscores the need for tailored clinical approaches in gender endocrinology to optimize GAHT outcomes among autistic TGD adults.