Highlights
- Nasal high flow (NHF) therapy during exercise in COPD modestly increases tidal volume (Vt) and reduces dyspnoea at submaximal exertion.
- NHF has negligible impact on dynamic respiratory muscle workload (PTPdi/min) and only a trivial improvement in endurance capacity.
- NHF may be most beneficial for patients with severe inspiratory constraints and pronounced dyspnoea during exercise.
Study Background and Disease Burden