Nasal High Flow Therapy During Exercise in COPD: Incremental Gains in Dyspnoea and Endurance

Highlights

• Nasal high flow (NHF) therapy during exercise in COPD modestly increases tidal volume (Vt) and reduces dyspnoea at submaximal exertion.
• NHF has negligible impact on dynamic respiratory muscle workload (PTPdi/min) and only a trivial improvement in endurance capacity.
• NHF may be most beneficial for patients with severe inspiratory constraints and pronounced dyspnoea during exercise.

Study Background and Disease Burden