Highlights
Genetic evidence suggests that higher GLP-1 receptor (GLP-1R) expression is causally linked to a reduced risk of both type 2 diabetes mellitus (T2DM) and myocardial infarction (MI).
The cardioprotective effects against MI are largely driven by metabolic improvements, specifically glycated hemoglobin (HbA1c), body mass index (BMI), triglyceride levels, and blood pressure.
