Background
The DETERMINE trial enrolled adult patients presenting with acute ischemic stroke secondary to anterior large vessel occlusion, indicated for mechanical thrombectomy (MT). The median age of participants was 69.3 years, with a slight female predominance (52.8%). Key inclusion parameters included radiological confirmation of anterior circulation large vessel occlusion and eligibility for MT as per established clinical protocols. Relevant medical histories varied, though demographic and baseline characteristics were balanced between groups.

