Highlights
The Baby-OSCAR trial investigated whether early selective treatment of a large patent ductus arteriosus (PDA) with ibuprofen improves clinical outcomes in extremely preterm infants.
Primary findings indicated no statistically significant difference in the composite outcome of death or moderate-to-severe bronchopulmonary dysplasia (BPD) at 36 weeks’ post-menstrual age between the ibuprofen and placebo groups.
