Highlight
• In the multicenter BMT CTN 1702 biological assignment trial, patients categorized as Very Unlikely (90%) to find a MUD.
• Among transplanted patients, MUD was used for 94% of the Very Likely group but only 9% of the Very Unlikely group; despite this distribution, relapse, treatment-related mortality, disease-free survival, and acute and chronic GVHD rates were similar across groups after multivariate adjustment.
